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魏贝尔-帕拉德小体与淋巴管内皮:对正常及炎症状态下人牙髓淋巴管的观察

Weibel-Palade bodies and lymphatic endothelium: observations in the lymphatic vessels of normal and inflamed human dental pulps.

作者信息

Marchetti C

机构信息

Istituto di Istologia ed Embriologia generale, Università di Pavia, Italia.

出版信息

Vasa. 1996;25(4):337-40.

PMID:8956550
Abstract

The Weibel-Palade bodies, cytoplasmic organelles characterizing endothelial cells, are abundant in lymphatic capillary endothelium of human dental pulp. Their number almost double in the lymphatic vessels of inflamed dental pulps. The data were discussed and compared with others concerning the demonstration of the presence of von Willebrand factor and P-selectin in the Weibel-Palade bodies of lymphatic vessels in mesentery. It is suggested that the increase in the number of Weibel-Palade bodies observed in dental pulp may be connected along with those in the lymphatic vessels to the function that these adhesive molecules play during inflammatory states.

摘要

魏尔-帕拉德小体是内皮细胞特有的细胞质细胞器,在人牙髓的淋巴管内皮中含量丰富。在发炎牙髓的淋巴管中,它们的数量几乎增加了一倍。对这些数据进行了讨论,并与其他关于肠系膜淋巴管的魏尔-帕拉德小体中血管性血友病因子和P-选择素存在情况的研究进行了比较。有人提出,牙髓中观察到的魏尔-帕拉德小体数量增加可能与淋巴管中的增加情况有关,与这些黏附分子在炎症状态下所起的作用有关。

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