Schroth G, Haldemann A R, Mariani L, Remonda L, Raveh J
Department of Neuroradiology, University of Bern, Switzerland.
Arch Otolaryngol Head Neck Surg. 1996 Dec;122(12):1320-5. doi: 10.1001/archotol.1996.01890240028007.
To determine if technetium Tc 99m-labeled macroaggregated albumin selective angioscintigraphy enables estimation of microparticle-arteriovenous shunt in branchial paragangliomas and nasopharyngeal angiofibromas.
Technetium Tc 99m-labeled macroaggregated albumin particles with calibrated diameters between 25 and 50 microns were administered during selective catheterization of the feeding arteries in 4 branchial paragangliomas (glomus tumors) and 4 nasopharyngeal angiofibromas. Preliminary measures of the activity of the tumor region and of the lungs were obtained in the angiography suite using a hand-held detector. Without changing the position of the microcatheter, definitive embolization was performed. After endovascular treatment, scintigraphy was performed and the pulmonary shunt index was calculated with the use of a gamma camera and a dedicated computer program.
The pulmonary shunt index varied between 0% and 36% for branchial paragangliomas (glomus tumors) and between 82% and 95% for angiofibromas.
Our results provide new evidence that the incidence of microparticle-arteriovenous shunt in nasopharyngeal angiofibromas is much higher than in paragangliomas.
确定锝 Tc 99m 标记的大颗粒白蛋白选择性血管闪烁造影术能否用于评估鳃旁神经节瘤和鼻咽血管纤维瘤中的微粒动静脉分流。
在对4例鳃旁神经节瘤（球瘤）和4例鼻咽血管纤维瘤的供血动脉进行选择性插管期间，注入直径校准在25至50微米之间的锝 Tc 99m 标记的大颗粒白蛋白颗粒。在血管造影室使用手持式探测器初步测量肿瘤区域和肺部的活性。在不改变微导管位置的情况下，进行确定性栓塞。血管内治疗后，进行闪烁造影，并使用伽马相机和专用计算机程序计算肺分流指数。
鳃旁神经节瘤（球瘤）的肺分流指数在0%至36%之间，血管纤维瘤的肺分流指数在82%至95%之间。
我们的结果提供了新的证据，表明鼻咽血管纤维瘤中微粒动静脉分流的发生率远高于副神经节瘤。
