Gregori-Romero M A, Morell-Quadreny L, Llombart-Bosch A
Department of Pathology, Medical School, University of Valencia, Spain.
Cancer Genet Cytogenet. 1996 Nov;92(1):28-30. doi: 10.1016/s0165-4608(96)00026-x.
Cytogenetic analysis of a human renal oncocytoma revealed a near-haploid chromosome number of 36 with the loss of chromosomes 1, 2, 3, 6, 8, 9, 15, 17, 21, and 22. Review of the literature disclosed that this cytogenetic configuration is extremely rare in solid human tumors and that no renal oncocytomas with near-haploid stemline karyotype have been described. These results are compared with the other published cases of oncocytoma.