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胃排空延迟:特纳综合征中一种新的胃肠道表现。

Delayed gastric emptying: a novel gastrointestinal finding in Turner's syndrome.

作者信息

Staiano A, Salerno M, Di Maio S, Marsullo G, Marino A, Concolino D, Strisciuglio P

机构信息

Department of Paediatrics, University Federico II, Naples, Italy.

出版信息

Arch Dis Child. 1996 Nov;75(5):440-3. doi: 10.1136/adc.75.5.440.

Abstract

AIM

To evaluate gastric emptying in girls with Turner's syndrome to detect if gastrointestinal motor dysfunction was present.

SUBJECTS

Thirteen girls (mean age 8.1 years) with Turner's syndrome, seven girls with familial short stature (6.1 years), and eight control girls (7.6 years).

METHODS

Gastric emptying studies were performed by using 500 microCi of technetium 99m-sulphur colloid bound to a scrambled egg, and scintigraphic measurements were made for 60 to 90 minutes.

RESULTS

Mean (SD) percentage retention of gastric isotope was significantly greater in girls with Turner's syndrome than in children with short stature and in controls. Furthermore, in contrast with control subjects, in whom there was an inverse linear relationship between gastric emptying rate and body mass index, in children with Turner's syndrome the delay in gastric emptying was independent of the body mass.

CONCLUSIONS

The results of the study suggest that delayed gastric emptying is detectable in girls with Turner's syndrome independent of age, body mass index, karyotype, and growth promoting treatment.

摘要

目的

评估特纳综合征女孩的胃排空情况,以检测是否存在胃肠运动功能障碍。

研究对象

13名特纳综合征女孩(平均年龄8.1岁)、7名家族性身材矮小的女孩(6.1岁)以及8名对照女孩(7.6岁)。

方法

采用500微居里与炒鸡蛋结合的锝99m - 硫胶体进行胃排空研究,并进行60至90分钟的闪烁扫描测量。

结果

特纳综合征女孩胃内同位素的平均(标准差)保留百分比显著高于身材矮小儿童和对照组。此外,与对照组不同,对照组胃排空率与体重指数呈负线性关系,而特纳综合征儿童胃排空延迟与体重无关。

结论

研究结果表明,特纳综合征女孩存在胃排空延迟,且与年龄、体重指数、核型及促生长治疗无关。

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