Uhde W J, Woggon H
Nahrung. 1977;21(5):377-84.
With a view to studying the possible use of methyltin compounds as PVC stabilizers in food industry, the authors elaborated a method for the thin-layer chromatographic and subsequent spectrophotometric or polarographic determination of mono-, di- and trimethyltin compounds in the stabilizer and after migration. Monmethyltin compounds are determined spectrophotometrically after reaction with quercetin. Dimethyltin compounds are incinerated by the wet method using sulphuric and nitric acids, and inorganic tin is then estimated polarographically. Prior to identification trimethyltin compounds must be converted into dimethyltin compounds by ultraviolet irradiation or by treatment with triethylamine and bromine. Corresponding to the different conditions of use, the authors investigated the migration of the methyltin stabilizer from PVC into distilled water, 3% acetic acid, 20% alcohol, 50% alcohol und Fettsimulans HB 307. They stated that its tendency to migration into foods is not greater than that of the octyltin stabilizer. The experimentally obtained migration values are discussed in connexion with toxicological data.
为了研究甲基锡化合物在食品工业中作为聚氯乙烯稳定剂的可能用途，作者制定了一种方法，用于对稳定剂中以及迁移后的一甲基锡、二甲基锡和三甲基锡化合物进行薄层色谱分析，随后进行分光光度法或极谱法测定。一甲基锡化合物与槲皮素反应后用分光光度法测定。二甲基锡化合物用硫酸和硝酸湿法灰化，然后用极谱法测定无机锡。在鉴定之前，三甲基锡化合物必须通过紫外线照射或用三乙胺和溴处理转化为二甲基锡化合物。对应于不同的使用条件，作者研究了甲基锡稳定剂从聚氯乙烯向蒸馏水、3%乙酸、20%乙醇、50%乙醇和脂肪模拟物HB 307中的迁移情况。他们指出，其向食品中的迁移倾向不大于辛基锡稳定剂。结合毒理学数据讨论了实验获得的迁移值。
