Nomura K, Takamura E, Murata M, Fukagawa K, Uechi K
Department of Ophthalmology, Tokyo Women's Medical College, Japan.
Ophthalmologica. 1997;211(1):1-3. doi: 10.1159/000310855.
This study aimed to investigate the inflammatory changes occurring in the allergic conjunctiva due to different allergens. Ninety-two allergic conjunctivitis patients were divided into two groups: group I showed cedar pollen sensitivity only; group II showed sensitivities to cedar pollen and household dust or mites. Using brush cytology procedures, quantitative evaluation of inflammatory cells in the conjunctiva was made. The mean proportion of the neutrophils and lymphocytes in group II was significantly higher than the percentage of neutrophils in group I. The counts of eosinophils showed no significant difference between groups I and II. Our results suggest that the eosinophil numbers are not different between the allergic conjunctivitis groups. The neutrophilic and lymphocytic increase in allergic conjunctivitis may be due to two distinct groups of antigens.
本研究旨在调查不同过敏原导致的过敏性结膜炎中的炎症变化。92例过敏性结膜炎患者被分为两组：第一组仅对雪松花粉敏感；第二组对雪松花粉以及家庭灰尘或螨虫敏感。采用刷片细胞学方法对结膜中的炎症细胞进行定量评估。第二组中性粒细胞和淋巴细胞的平均比例显著高于第一组中性粒细胞的百分比。第一组和第二组之间嗜酸性粒细胞计数无显著差异。我们的结果表明，过敏性结膜炎组之间嗜酸性粒细胞数量没有差异。过敏性结膜炎中中性粒细胞和淋巴细胞的增加可能是由于两组不同的抗原所致。
