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Human interleukin-12 upregulates proliferation and interferon-gamma production by parasite antigen-stimulated Th cell clones and gamma/delta T cells of cattle.

作者信息

Brown W C, Davis W C, Tuo W

机构信息

Department of Veterinary Microbiology and Pathology, Washington State University, Pullman 99164-7040, USA.

出版信息

Ann N Y Acad Sci. 1996 Oct 31;795:321-4. doi: 10.1111/j.1749-6632.1996.tb52682.x.

DOI:10.1111/j.1749-6632.1996.tb52682.x
PMID:8958944
Abstract
摘要

相似文献

1
Human interleukin-12 upregulates proliferation and interferon-gamma production by parasite antigen-stimulated Th cell clones and gamma/delta T cells of cattle.
Ann N Y Acad Sci. 1996 Oct 31;795:321-4. doi: 10.1111/j.1749-6632.1996.tb52682.x.
2
Interleukin-10 is expressed by bovine type 1 helper, type 2 helper, and unrestricted parasite-specific T-cell clones and inhibits proliferation of all three subsets in an accessory-cell-dependent manner.白细胞介素-10由牛1型辅助性T细胞、2型辅助性T细胞和不受限制的寄生虫特异性T细胞克隆表达,并以辅助细胞依赖的方式抑制所有这三个亚群的增殖。
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Bovine CD4(+) T-lymphocyte clones specific for rhoptry-associated protein 1 of Babesia bigemina stimulate enhanced immunoglobulin G1 (IgG1) and IgG2 synthesis.针对双芽巴贝斯虫动基体相关蛋白1的牛CD4(+) T淋巴细胞克隆刺激免疫球蛋白G1(IgG1)和IgG2合成增强。
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CD4+ T-cell clones obtained from cattle chronically infected with Fasciola hepatica and specific for adult worm antigen express both unrestricted and Th2 cytokine profiles.从长期感染肝片吸虫的牛体内获得的、对成虫抗原具有特异性的CD4 + T细胞克隆表达无限制的和Th2细胞因子谱。
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Interleukin-10 downregulates proliferation and expression of interleukin-2 receptor p55 chain and interferon-gamma, but not interleukin-2 or interleukin-4, by parasite-specific helper T cell clones obtained from cattle chronically infected with Babesia bovis or Fasciola hepatica.白细胞介素-10可下调从长期感染牛巴贝斯虫或肝片吸虫的牛体内获得的寄生虫特异性辅助性T细胞克隆的增殖以及白细胞介素-2受体p55链和干扰素-γ的表达,但不会下调白细胞介素-2或白细胞介素-4的表达。
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Babesia bovis-stimulated macrophages express interleukin-1beta, interleukin-12, tumor necrosis factor alpha, and nitric oxide and inhibit parasite replication in vitro.牛巴贝斯虫刺激的巨噬细胞表达白细胞介素-1β、白细胞介素-12、肿瘤坏死因子α和一氧化氮,并在体外抑制寄生虫复制。
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Interleukin-12 as an adjuvant promotes immunoglobulin G and type 1 cytokine recall responses to major surface protein 2 of the ehrlichial pathogen Anaplasma marginale.白细胞介素-12作为佐剂可促进对埃立克体病原体边缘无形体主要表面蛋白2的免疫球蛋白G和1型细胞因子回忆反应。
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Regulation of bovine leukemia virus tax and pol mRNA levels by interleukin-2 and -10.
白细胞介素-2和-10对牛白血病病毒tax和pol mRNA水平的调控
J Virol. 1999 Oct;73(10):8427-34. doi: 10.1128/JVI.73.10.8427-8434.1999.
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DNA and a CpG oligonucleotide derived from Babesia bovis are mitogenic for bovine B cells.来自牛巴贝斯虫的DNA和一种CpG寡核苷酸对牛B细胞具有促有丝分裂作用。
Infect Immun. 1998 Nov;66(11):5423-32. doi: 10.1128/IAI.66.11.5423-5432.1998.