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A novel ets-2-related nuclear factor is involved in transcriptional activation of the human interleukin-12 p40 gene promoter in response to interferon-gamma and LPS stimulation of monocytic cells.

作者信息

Ma X, Gri G, Trinchieri G

机构信息

Wistar Institute, Philadelphia, Pennsylvania 19104, USA.

出版信息

Ann N Y Acad Sci. 1996 Oct 31;795:357-60. doi: 10.1111/j.1749-6632.1996.tb52692.x.

DOI:10.1111/j.1749-6632.1996.tb52692.x
PMID:8958954
Abstract
摘要

相似文献

1
A novel ets-2-related nuclear factor is involved in transcriptional activation of the human interleukin-12 p40 gene promoter in response to interferon-gamma and LPS stimulation of monocytic cells.
Ann N Y Acad Sci. 1996 Oct 31;795:357-60. doi: 10.1111/j.1749-6632.1996.tb52692.x.
2
Identification and characterization of a novel Ets-2-related nuclear complex implicated in the activation of the human interleukin-12 p40 gene promoter.一种与人类白细胞介素-12 p40基因启动子激活相关的新型Ets-2相关核复合物的鉴定与表征。
J Biol Chem. 1997 Apr 18;272(16):10389-95. doi: 10.1074/jbc.272.16.10389.
3
An IFN-gamma-inducible transcription factor, IFN consensus sequence binding protein (ICSBP), stimulates IL-12 p40 expression in macrophages.一种γ干扰素诱导的转录因子，即干扰素共有序列结合蛋白（ICSBP），可刺激巨噬细胞中白细胞介素-12 p40的表达。
J Immunol. 2000 Jul 1;165(1):271-9. doi: 10.4049/jimmunol.165.1.271.
4
The interleukin 12 p40 gene promoter is primed by interferon gamma in monocytic cells.白细胞介素12 p40基因启动子在单核细胞中由γ干扰素启动。
J Exp Med. 1996 Jan 1;183(1):147-57. doi: 10.1084/jem.183.1.147.
5
Synergistic regulation of the human interleukin-12 p40 promoter by NFkappaB and Ets transcription factors in Epstein-Barr virus-transformed B cells and macrophages.EB病毒转化的B细胞和巨噬细胞中NFκB和Ets转录因子对人白细胞介素-12 p40启动子的协同调控
J Biol Chem. 1998 Mar 13;273(11):6431-8. doi: 10.1074/jbc.273.11.6431.
6
Suppression of Il-12 transcription in macrophages following Fc gamma receptor ligation.Fcγ受体连接后巨噬细胞中白细胞介素-12转录的抑制。
J Immunol. 2001 Apr 1;166(7):4498-506. doi: 10.4049/jimmunol.166.7.4498.
7
Regulation of IL-12 p40 promoter activity in primary human monocytes: roles of NF-kappaB, CCAAT/enhancer-binding protein beta, and PU.1 and identification of a novel repressor element (GA-12) that responds to IL-4 and prostaglandin E(2).原代人单核细胞中白细胞介素-12 p40启动子活性的调控：核因子-κB、CCAAT/增强子结合蛋白β和PU.1的作用以及对白细胞介素-4和前列腺素E2有反应的新型抑制元件（GA-12）的鉴定
J Immunol. 2001 Sep 1;167(5):2608-18. doi: 10.4049/jimmunol.167.5.2608.
8
Differential regulation of interleukin (IL)-12 p35 and p40 gene expression and interferon (IFN)-gamma-primed IL-12 production by IFN regulatory factor 1.干扰素调节因子1对白细胞介素（IL）-12 p35和p40基因表达以及干扰素（IFN）-γ启动的IL-12产生的差异调节
J Exp Med. 2003 Oct 20;198(8):1265-76. doi: 10.1084/jem.20030026.
9
CpG DNA induced IL-12 p40 gene activation is independent of STAT1 activation or production of interferon consensus sequence binding protein.CpG DNA诱导的IL-12 p40基因激活独立于STAT1激活或干扰素共有序列结合蛋白的产生。
J Biomed Sci. 2002 Nov-Dec;9(6 Pt 2):688-96. doi: 10.1159/000067280.
10
ATF and Jun transcription factors, acting through an Ets/CRE promoter module, mediate lipopolysaccharide inducibility of the chemokine RANTES in monocytic Mono Mac 6 cells.ATF和Jun转录因子通过Ets/CRE启动子模块发挥作用，介导单核细胞系Mono Mac 6细胞中趋化因子RANTES的脂多糖诱导性。
Eur J Immunol. 2000 Apr;30(4):1102-12. doi: 10.1002/(SICI)1521-4141(200004)30:4<1102::AID-IMMU1102>3.0.CO;2-X.

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Disruption of MAP kinase activation and nuclear factor binding to the IL-12 p40 promoter in HIV-infected myeloid cells.HIV感染的髓样细胞中MAP激酶激活及核因子与IL-12 p40启动子结合的破坏。
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Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cells.
树突状细胞介导的回肠末端组成型p40启动子激活及白细胞介素-23产生
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