Koláŏvá M
Neoplasma. 1977;24(3):285-90.
Current determinations of the hyaluronidase activity and hyaluronidase inhibitor in the serum of patients with a tumor disease failed to show a correlation between a lowered hyaluronidase activity and increased inhibitor level. The serum fraction that contained the inhibitor and which had been obtained by gel filtration of Sephadex G-200 had no in vitro inhibitory effect on the serum fraction containing hyaluronidase. Hence, the decreased serum hyaluronidase activity in these patients is not due to an increased levles of hyaluronidase inhibitor.
目前对肿瘤疾病患者血清中透明质酸酶活性和透明质酸酶抑制剂的测定未能显示出透明质酸酶活性降低与抑制剂水平升高之间的相关性。通过Sephadex G - 200凝胶过滤获得的含有抑制剂的血清组分对含有透明质酸酶的血清组分没有体外抑制作用。因此，这些患者血清透明质酸酶活性降低并非由于透明质酸酶抑制剂水平升高所致。
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