Niebrój-Dobosz I, Rowińska-Marcińska K, Dembek I
Neurol Neurochir Pol. 1977 Jul-Aug;11(4):421-6.
Serum lipids were determined in 40 cases of polyneuropathy including 17 cases of Charcot-Marie-Tooth peroneal muscular atrophy, 7 cases of Dejerine-Sot-tas polyneuropathy, 7 cases of Guillain-Barré syndrome, 2 cases of diabetic polyneuropathy, 2 cases of toxic polyneuropathy and 5 cases of polyneuropathy of unclear aetiology. In the studied material shifts were observed in the composition of serum lipids, in particular, sphingomyelin and cholesterol esters. No correlation was found beteen the type of lipid pattern changes and the clinical syndrome, type of histological changes in the sural nerve, the age at onset, as well as the duration of the disease. The probable mechanism of development of changes is discussed.
对40例多发性神经病患者进行了血脂测定，其中包括17例夏科-马里-图斯型腓骨肌萎缩症、7例德热里纳-索塔斯型多发性神经病、7例吉兰-巴雷综合征、2例糖尿病性多发性神经病、2例中毒性多发性神经病以及5例病因不明的多发性神经病。在所研究的材料中，观察到血清脂质成分发生了变化，尤其是鞘磷脂和胆固醇酯。未发现脂质模式变化类型与临床综合征、腓肠神经组织学变化类型、发病年龄以及病程之间存在相关性。文中讨论了变化发生的可能机制。
