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新加坡一家皮肤转诊中心的光皮肤病

Photodermatoses in a Singapore skin referral centre.

作者信息

Khoo S W, Tay Y K, Tham S N

机构信息

National Skin Centre, Singapore.

出版信息

Clin Exp Dermatol. 1996 Jul;21(4):263-8. doi: 10.1111/j.1365-2230.1996.tb00090.x.

Abstract

The inducing or exacerbating effect of sunlight on skin diseases is often not appreciated in tropical countries, perhaps because of the perennial presence of sunlight, and a retrospective review of photodermatoses seen in a referral skin clinic was therefore carried out. The photodermatoses seen were secondary photoaggravation of primary skin diseases (32.2%), systemic drug photosensitivity (11.3%), polymorphic light eruption (13%), chronic actinic dermatitis (5.3%), solar urticaria (5.3%), actinic prurigo (4%), photoallergic contact dermatitis (2.6%), porphyria (1.3%) and xeroderma pigmentosum (1.3%). Compared with the results of Western studies, there were more photoaggravated underlying skin diseases and systemic drug photosensitivity, and fewer idiopathic photodermatoses and photoallergic contact dermatitis; the common photoallergens were chlorpromazine, promethazine and musk ambrette, very similar to those seen in the West.

摘要

在热带国家,阳光对皮肤病的诱发或加重作用常常未得到重视,这可能是由于阳光常年存在,因此我们对一家转诊皮肤诊所中所见的光皮肤病进行了回顾性研究。所见的光皮肤病包括原发性皮肤病的继发性光加重(32.2%)、系统性药物光敏反应(11.3%)、多形性日光疹(13%)、慢性光化性皮炎(5.3%)、日光性荨麻疹(5.3%)、光化性痒疹(4%)、光变应性接触性皮炎(2.6%)、卟啉病(1.3%)和着色性干皮病(1.3%)。与西方研究结果相比,光加重的潜在皮肤病和系统性药物光敏反应更多,特发性光皮肤病和光变应性接触性皮炎更少;常见的光变应原是氯丙嗪、异丙嗪和葵子麝香,与西方所见非常相似。

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