Khoo S W, Tay Y K, Tham S N
National Skin Centre, Singapore.
Clin Exp Dermatol. 1996 Jul;21(4):263-8. doi: 10.1111/j.1365-2230.1996.tb00090.x.
The inducing or exacerbating effect of sunlight on skin diseases is often not appreciated in tropical countries, perhaps because of the perennial presence of sunlight, and a retrospective review of photodermatoses seen in a referral skin clinic was therefore carried out. The photodermatoses seen were secondary photoaggravation of primary skin diseases (32.2%), systemic drug photosensitivity (11.3%), polymorphic light eruption (13%), chronic actinic dermatitis (5.3%), solar urticaria (5.3%), actinic prurigo (4%), photoallergic contact dermatitis (2.6%), porphyria (1.3%) and xeroderma pigmentosum (1.3%). Compared with the results of Western studies, there were more photoaggravated underlying skin diseases and systemic drug photosensitivity, and fewer idiopathic photodermatoses and photoallergic contact dermatitis; the common photoallergens were chlorpromazine, promethazine and musk ambrette, very similar to those seen in the West.
在热带国家，阳光对皮肤病的诱发或加重作用常常未得到重视，这可能是由于阳光常年存在，因此我们对一家转诊皮肤诊所中所见的光皮肤病进行了回顾性研究。所见的光皮肤病包括原发性皮肤病的继发性光加重（32.2%）、系统性药物光敏反应（11.3%）、多形性日光疹（13%）、慢性光化性皮炎（5.3%）、日光性荨麻疹（5.3%）、光化性痒疹（4%）、光变应性接触性皮炎（2.6%）、卟啉病（1.3%）和着色性干皮病（1.3%）。与西方研究结果相比，光加重的潜在皮肤病和系统性药物光敏反应更多，特发性光皮肤病和光变应性接触性皮炎更少；常见的光变应原是氯丙嗪、异丙嗪和葵子麝香，与西方所见非常相似。
