Hurt H, Brodsky N L, Betancourt L, Braitman L E, Belsky J, Giannetta J
Division of Neonatology, Albert Einstein Medical Center, Temple University School of Medicine, Philadelphia, PA 19141, USA.
J Dev Behav Pediatr. 1996 Dec;17(6):373-9. doi: 10.1097/00004703-199612000-00001.
Play behavior was compared between toddlers with in utero cocaine exposure and controls of similar low socioeconomic status enrolled at birth in a prospective, masked study. At 18 and 24 months, 83 cocaine-exposed and 93 control toddlers were videotaped playing on their own for 15 minutes. An observer who was off-site and unaware of project purpose or drug exposure status of toddlers recorded the most cognitively complex play activity per 15-second interval. In a total of 315 play sessions, the groups did not differ in middle and highest level of play achieved at either 18 or 24 months (p > or = .27). After controlling for confounders, the proportions of play behavior in each of six play categories were similar in the two groups at both 18 and 24 months (p > or = .42). We conclude that in utero cocaine exposure was not associated with differences in play behavior in this cohort of cocaine-exposed and control toddlers.
在一项前瞻性、盲法研究中，对子宫内接触可卡因的幼儿与出生时登记的社会经济地位相似的低水平对照组幼儿的游戏行为进行了比较。在18个月和24个月时，对83名接触可卡因的幼儿和93名对照幼儿进行了15分钟的独自玩耍录像。一名不在现场且不知道项目目的或幼儿药物接触状况的观察者记录了每15秒间隔内认知最复杂的游戏活动。在总共315次游戏环节中，两组在18个月或24个月时达到的中等和最高游戏水平没有差异（p≥0.27）。在控制了混杂因素后，两组在18个月和24个月时六个游戏类别中每个类别的游戏行为比例相似（p≥0.42）。我们得出结论，在这组接触可卡因的幼儿和对照幼儿中，子宫内接触可卡因与游戏行为差异无关。
