雌激素、孕酮及其拮抗剂对妊娠大鼠子宫中胶原蛋白含量的影响。
The influence of estrogens, progesterone and their antagonists on the collagen content in the pregnant rat uterus.
作者信息
Bieńkiewicz A, Welfel J, Kuś E
机构信息
Department of Pathophysiology, Medical University of Lódź, Poland.
出版信息
Horm Metab Res. 1996 Nov;28(11):592-4. doi: 10.1055/s-2007-979859.
The influence of progesterone, estrogens and their antagonists: mifepristone and tamoxifen on connective tissue metabolism in pregnant rat uterus near term was evaluated. Total collagen and its soluble fraction as well as water concentration was measured in a population of 65 pregnant rats; treated with progesterone (n = 10), mifepristone (n = 13), estradiol (n = 17) and tamoxifen (n = 12). The results suggest the important influence of sex steroids on the uterine connective tissue metabolism during pregnancy.
评估了孕酮、雌激素及其拮抗剂米非司酮和他莫昔芬对近足月妊娠大鼠子宫结缔组织代谢的影响。对65只妊娠大鼠进行了测量，分别用孕酮（n = 10）、米非司酮（n = 13）、雌二醇（n = 17）和他莫昔芬（n = 12）处理，测量了总胶原蛋白及其可溶性部分以及水分含量。结果表明，性类固醇在妊娠期间对子宫结缔组织代谢有重要影响。
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