高同型半胱氨酸血症是精神分裂症的一个常见特征。
Homocysteinemia is a common feature of schizophrenia.
作者信息
Regland B, Johansson B V, Grenfeldt B, Hjelmgren L T, Medhus M
机构信息
Department of Clinical Neuroscience, Göteborg University, Sweden.
出版信息
J Neural Transm Gen Sect. 1995;100(2):165-9. doi: 10.1007/BF01271539.
PMID:8962686
Abstract
A significant proportion of patients with schizophrenia have increased homocysteine levels that are unrelated to psychopharmacological medication or nutrient deficiency in folate or cobalamin. This supports the hypothesis that inherent methylation deficiency is involved in the pathogenesis of schizophrenia.
摘要
相当一部分精神分裂症患者的同型半胱氨酸水平升高，这与精神药物治疗或叶酸或钴胺素的营养缺乏无关。这支持了内在甲基化缺陷参与精神分裂症发病机制的假说。
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