Garkavi L Kh, Kvakina E B, Shikhliarova A I, Kuz'menko T S, Barsukova L P, Mar'ianovskaia G Ia, Sheĭka E A, Evstratova O F, Zhukova G V
Biofizika. 1996 Jul-Aug;41(4):898-905.
It is shown that general nonspecific adaptational reactions are the basis for mechanism of magnetic field effects at the organism level. The character of changes in organism and its subsystems (pattern of a general nonspecific adaptational reactions) is determined by the type of the reaction developing under magnetic field: stress or unknown before antistress reactions of training, calm activation and enhanced activation. The protection and damages under stress are interwoven, homeostatic parameters go beyond norm. Patterns of antistress general nonspecific adaptational reactions are within norm: for training reaction-within the lower half, calm activation-upper half, enhanced activation-somewhat above norm. The induction and frequency dependence of the reactions is periodical: as the parameters are changed to a certain coefficient a regular reiteration of general nonspecific adaptational reactions as topologically invariant transformations is observed at different reactivity levels of organism. General nonspecific adaptational reactions of superior reactivity levels (under weak of magnetic fields of lowest frequency) are more favourable, general nonspecific adaptational reactions of low levels have features of strain, desynchronization. Antistress general nonspecific adaptational reactions, especially activation reaction of superior reactivity levels, enhance nonspecific resistance, in contrast to stress without any damages or waste of energy, produce antitumor, protective (in reference to toxic agents and X-radiation) and rejuvenation effects, promoting self-organization. Regularities of general nonspecific adaptational reactions correspond to complex unequilibrium systems behavior.
研究表明,一般非特异性适应性反应是磁场在机体水平产生效应的机制基础。机体及其子系统变化的特征(一般非特异性适应性反应模式)由磁场作用下所产生反应的类型决定:应激反应或训练前未知的抗应激反应、平静激活和增强激活。应激状态下的保护与损伤相互交织,稳态参数超出正常范围。抗应激一般非特异性适应性反应模式在正常范围内:训练反应处于下半区,平静激活处于上半区,增强激活略高于正常范围。反应的诱导和频率依赖性是周期性的:当参数变化到一定系数时,在机体不同反应水平上可观察到一般非特异性适应性反应作为拓扑不变变换的规律重复。较高反应水平(在最低频率的弱磁场作用下)的一般非特异性适应性反应更有利,低水平的一般非特异性适应性反应具有应激、去同步化的特征。抗应激一般非特异性适应性反应,尤其是较高反应水平的激活反应,可增强非特异性抵抗力,与无任何损伤或能量消耗的应激反应不同,具有抗肿瘤、保护(针对有毒物质和X射线)和恢复活力的作用,促进自组织。一般非特异性适应性反应规律与复杂的非平衡系统行为相对应。