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[使用或不使用奥曲肽及肠外营养治疗肠皮肤瘘]

[Treatment of enterocutaneous fistula with or without octreotide and parenteral nutrition].

作者信息

Hernández-Aranda J C, Gallo-Chico B, Flores-Ramírez L A, Avalos-Huante R, Magos-Vázquez F J, Ramírez-Barba E J

机构信息

Instituto Mexicano del Seguro Social, Centro Médico Nacional León, Hospital de Especialidades, México.

出版信息

Nutr Hosp. 1996 Jul-Aug;11(4):226-9.

PMID:8962902
Abstract

OBJECTIVE

To evaluate the use of octreotide together with the conservative handling in the treatment of patients with external gastrointestinal fistulae.

MATERIAL AND METHODS

Clinical essay in postsurgical gastrointestinal fistulae carriers assisted during a 54-month period. They were randomly distributed in two groups: group A was treated with conventional handling and group B was additionally treated with octreotide.

RESULTS

44 women and 55 men with an average age of 50 +/- 19 years old were treated. The following table summarizes the result variables. [table: see text]

CONCLUSION

The use of octreotide is recommendable, for it was useful in diminishing both the closing time of the fistula and the time the nutritional support the patient requires. Mortality still continues to be very increased (because of sepsis), by which the phrase "primum non nocere" takes a relevant place since this pathology is greatly preventable.

摘要

目的

评估奥曲肽联合保守治疗在胃肠道外瘘患者治疗中的应用。

材料与方法

对54个月期间接受治疗的术后胃肠道瘘患者进行临床研究。他们被随机分为两组:A组采用传统治疗,B组额外加用奥曲肽治疗。

结果

共治疗了44名女性和55名男性,平均年龄为50±19岁。下表总结了结果变量。[表格:见正文]

结论

推荐使用奥曲肽,因为它有助于缩短瘘管闭合时间以及患者所需营养支持的时间。死亡率仍然很高(由于败血症),鉴于这种疾病是可预防的,“首要的是不伤害”这一原则在此具有重要意义。

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