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[重度穿透性枪伤性颅脑创伤中的大脑皮质(一项实验研究)]

[The cerebral cortex in severe penetrating gunshot craniocerebral trauma (an experimental study)].

作者信息

Novozhilova A P, Dyskin E A, Isakov V D, Kolkutin V V

出版信息

Morfologiia. 1996;109(2):17-22.

PMID:8963410
Abstract

Gunshot disturbances of different severeness were induced in rabbit brain by means of specifically worked out experimental model. Cerebral cortex was studied using light and electron microscopy in severe gunshot craniocerebral trauma (SGCT), accompanied with cranial bones and cerebral disorders, plentiful external and internal hemorrhages and death of the animals 1-5 minutes after the shot. Peculiarities of responsiveness to trauma were demonstrated in microcirculatory bed elements, neurons and glial cells. SGCT causes rapid appearance of destructive changes in cerebral cortex with degenerative processes not following hemomicrocirculatory bed disturbances, but developing simultaneously with them.

摘要

通过专门设计的实验模型,在兔脑内诱发不同严重程度的枪伤干扰。采用光镜和电镜对重度颅脑枪伤(SGCT)进行研究,此类损伤伴有颅骨和脑功能紊乱、大量内外出血,动物在枪击后1 - 5分钟死亡。在微循环床成分、神经元和神经胶质细胞中表现出对创伤反应的特殊性。重度颅脑枪伤导致大脑皮质迅速出现破坏性变化,退行性过程并非继发于血液微循环床紊乱,而是与之同时发生。

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