Shmuter L M, Kleĭner A I, Makotchenko V M, Genes V S, Trukh V S
Klin Lab Diagn. 1993 May-Jun(3):32-9.
Studies of the immunity in 233 patients with dust-induced bronchitis (DIB), engaged in machine building, have revealed essential shifts in the T and B immunity systems, that were related to the severity and clinical features of the disease. The authors have set up the criteria for defining the normal range of values and the range of immunologic values characteristic of DIB; this helped detect the disordered immunity parameters in each of the examined patients. A method for the diagnosis of the immunity disorders in DIB patients is suggested, making use of just two characteristics, the per cent share of active T and B lymphocytes and their ratio, this essentially simplifying and accelerating the investigation.
对233名从事机械制造、患有粉尘性支气管炎(DIB)患者的免疫研究发现,T和B免疫系统发生了显著变化,这些变化与疾病的严重程度和临床特征相关。作者制定了定义正常数值范围以及DIB特征性免疫数值范围的标准;这有助于检测每名受检患者的免疫参数紊乱情况。提出了一种诊断DIB患者免疫紊乱的方法,该方法仅利用两个特征,即活性T和B淋巴细胞的百分比及其比例,这在本质上简化并加速了调查。