Kalski R S, Sutton G, Bin Y, Lawless M A, Rogers C
Sydney Refractive Surgery Centre, St. Leonards, NSW, Australia.
J Refract Surg. 1996 Jan-Feb;12(1):61-7. doi: 10.3928/1081-597X-19960101-13.
Variation in ablation zone diameter may alter visual acuity and/or refractive effect in photorefractive keratectomy. Despite theoretical benefits of using a smaller diameter ablation zone, clinical studies suggest that a larger ablation zone may decrease problems associated with photorefractive keratectomy.
The results of our initial 34 consecutive eyes treated with a 5-mm diameter ablation zone using a Summit Technology ExciMed UV200LA excimer laser were compared retrospectively to our initial 34 consecutive eyes treated with a 6-mm diameter ablation zone using a Summit OmniMed excimer laser. Eyes had a spherical equivalent refraction between -1.00 and -6.00 diopters (D) and astigmatism less than 1.00 D. Patients were followed for a minimum of 6 months.
Eyes treated with a 6-mm ablation zone had less hyperopia and a spherical equivalent refraction closer to emmetropia at 1, 2, and 3 months (P = 0.001). Eyes treated with a 6-mm ablation zone had better uncorrected visual acuity at 1 and 2 months (P = 0.001). Less subepithelial haze was noted at 2 months (P = 0.01) and 3 months (P = 0.002) in the 6-mm group. At 6 months postoperatively, 30 of 32 eyes (94%) treated with a 6-mm ablation zone had a spherical equivalent refraction within 0.50 D of emmetropia, and all 32 eyes (100%) were within 1.00 D of emmetropia; in the 5-mm ablation zone group, 28 of 34 eyes (80%) were within 0.50 D and 29 (85%) were within 1.00 D of emmetropia. Patients treated with a 6-mm ablation zone complained less of night halos and had fewer differences between night and day vision.
In this study of myopia of -1.00 D to -6.00 D, eyes treated with a 6-mm ablation zone achieve a more rapid visual recovery with less variation in refractive outcome and less adverse effects than those treated with a 5-mm ablation zone.
在准分子激光原位角膜磨镶术(PRK)中,消融区直径的变化可能会改变视力和/或屈光效果。尽管使用较小直径的消融区理论上有好处,但临床研究表明,较大直径的消融区可能会减少与PRK相关的问题。
回顾性比较我们最初连续治疗的34只眼睛,其中一组使用Summit Technology ExciMed UV200LA准分子激光进行5毫米直径的消融区治疗,另一组使用Summit OmniMed准分子激光进行6毫米直径的消融区治疗。眼睛的等效球镜度在-1.00至-6.00屈光度(D)之间,散光小于1.00 D。患者至少随访6个月。
接受6毫米消融区治疗的眼睛在1、2和3个月时远视程度较轻,等效球镜度更接近正视(P = 0.001)。接受6毫米消融区治疗的眼睛在1和2个月时裸眼视力更好(P = 0.001)。6毫米组在2个月(P = 0.01)和3个月(P = 0.002)时观察到的上皮下混浊较少。术后6个月时,接受6毫米消融区治疗的32只眼睛中有30只(94%)的等效球镜度在正视眼的0.50 D范围内,所有32只眼睛(100%)在正视眼的1.00 D范围内;在5毫米消融区组中,34只眼睛中有28只(80%)在0.50 D范围内,29只(85%)在正视眼的1.00 D范围内。接受6毫米消融区治疗的患者较少抱怨夜间光晕,昼夜视力差异也较小。
在这项对-1.00 D至-6.00 D近视的研究中,与接受5毫米消融区治疗的眼睛相比,接受6毫米消融区治疗的眼睛视力恢复更快,屈光结果变化更小,不良反应更少。