Ghisletta N, von Flüe M, Eichlisberger E, Brühwiler I, Ritz R, Harder F
Departement Chirurgie, Allgemeinchirurgische Klinik, Universitätsspital Basel.
Swiss Surg. 1996;2(5):223-9.
The mesenterial venous thrombosis is a rare and independent cause of intestinal ischemia. 5 to 15% of all intestinal ischemias are due to venous problems. The lack of specific clinical symptoms and laboratory data often leads to a delayed diagnosis with irreversible intestinal infarction. Only by thorough searching by means of modern diagnostic devices is it possible to make an early diagnosis and treat the ischemic situation timely. Several therapeutical options are at hand. A timely and adequate application of these aids mostly depends on the clinical experience of the medical team as well as on an optimal interdisciplinary collaboration (radiology, hematology, angiology, gastroenterology, surgery). We want to analyze the problems related to diagnostics and management on the basis of 2 cases with different manifestations of a mesenterial venous thrombosis. We ascertain that: (1) the enhanced-CT analysis and/or the duplex-sonography mostly lead to a diagnosis, (2) the prognosis benefits from an immediate heparinization, (3) the request for large-scale intestinal resection, keeping a safety-space, has been replaced by the technique of limited resection, followed by earlier second-look-operations.
肠系膜静脉血栓形成是肠道缺血的一种罕见且独立的病因。所有肠道缺血病例中,5%至15%是由静脉问题所致。缺乏特异性临床症状和实验室数据常常导致诊断延迟,进而引发不可逆转的肠梗死。只有借助现代诊断设备进行全面检查,才有可能早期诊断并及时治疗缺血情况。现有多种治疗选择。这些辅助手段的及时、恰当应用很大程度上取决于医疗团队的临床经验以及最佳的多学科协作(放射学、血液学、血管学、胃肠病学、外科学)。我们想基于2例表现不同的肠系膜静脉血栓形成病例来分析诊断和治疗方面的问题。我们确定:(1)增强CT分析和/或双功超声检查大多能得出诊断结果;(2)立即进行肝素化治疗对预后有益;(3)要求进行大范围肠切除并保留安全切缘的做法已被有限切除技术所取代,随后进行早期二次探查手术。