Litzman J
Ustav klinické imunologie LF MU, FN u sv. Anny, Brno.
Cas Lek Cesk. 1996 Sep 11;135(17):552-4.
The possibilities of the influence of the immune system in patients with primary immunodeficiencies are nowadays limited. Bone marrow transplantation is the only causal treatment at present, but it is used only in patients with the most severe diseases. Gene transplantation is a possible approach in diseases with known genetic defects, but the experience is still very limited. As a replacement therapy, immunoglobulin is the most frequently used, while enzyme replacement therapy has only a restricted applicability. Adequate antibiotic therapy is an essential part of the treatment of the patients with primary immunodeficiencies, both as an adequate and rasant antibiotic treatment of acute infections and also as a long-term antibacterial, and in some cases also anti-viral and anti-fungal prophylaxis.
目前，免疫系统对原发性免疫缺陷患者的影响可能性有限。骨髓移植是目前唯一的病因治疗方法，但仅用于患有最严重疾病的患者。基因移植是治疗已知遗传缺陷疾病的一种可能方法，但经验仍然非常有限。作为替代疗法，免疫球蛋白是最常用的，而酶替代疗法的适用性有限。适当的抗生素治疗是原发性免疫缺陷患者治疗的重要组成部分，既是对急性感染的充分且迅速的抗生素治疗，也是长期的抗菌治疗，在某些情况下还是抗病毒和抗真菌预防。
