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[使用β-肾上腺素能阻滞剂对钙对心脏作用的影响进行的修饰]

[The modification of the effects of calcium on the heart using beta-adrenergic blockers].

作者信息

Hapke H J, Frank I

机构信息

Institut für Pharmakologie, Toxikologie und Pharmazie, Tierärztlichen Hochschule Hannover.

出版信息

Dtsch Tierarztl Wochenschr. 1996 May;103(5):170-4.

PMID:8964238
Abstract

To reduce unwanted effects of calcium upon the heart, in particular in cows during the treatment of hypocalcaemia, experiments were carried out in isolated hearts of guinea pigs and in conscious rabbits, to show whether beta-adrenergic blocking agents are able to antagonize these effects. It was found that calcium effects in the second phase which is characterized by a tachycardia, are antagonized by carazolol, which was used for these experiments.

摘要

为了减少钙对心脏的不良影响,特别是在治疗奶牛低钙血症期间,在豚鼠离体心脏和清醒兔身上进行了实验,以表明β-肾上腺素能阻滞剂是否能够拮抗这些影响。结果发现,在以心动过速为特征的第二阶段,钙的影响可被用于这些实验的卡拉洛尔所拮抗。

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