Shadrina M I, Slonimskiĭ P A, Oganov R G, Perova N V, Limborskaia S A
Genetika. 1996 Aug;32(8):1041-4.
Comparative analysis of polymorphism of two polymorphic regions in the 5'-end of the apolipoprotein B gene-insertion/ deletion polymorphism of a signal peptide of apo B and microsatellite (CA)n repeat-was performed in a random sample of men from the Moscow population aged 49-51 and in heart patients. No associations among the gene polymorphic regions, development of coronary heart disease, and certain changes in the lipid spectrum of plasma are revealed. This indicates that the structural organization of the 5'-region of apolipoprotein gene B (Moscow population) has no substantial role in determining the risk of coronary heart disease.
对来自莫斯科人群中49 - 51岁男性的随机样本以及心脏病患者，进行了载脂蛋白B基因5'端两个多态性区域多态性的比较分析——载脂蛋白B信号肽的插入/缺失多态性和微卫星(CA)n重复序列。未发现基因多态性区域、冠心病的发展与血浆脂质谱某些变化之间存在关联。这表明载脂蛋白B基因5'区域的结构组织（莫斯科人群）在确定冠心病风险方面没有实质性作用。
