Blomstedt G C, Katila H, Henriksson M, Ekholm A, Jääskeläinen J E, Pyykko I
Department of Neurosurgerey, Helsinki University Central Hospital, Finland
J Neurol Neurosurg Psychiatry. 1996 Oct;61(4):403-6. doi: 10.1136/jnnp.61.4.403.
The purpose of this study was to establish the frequency and pattern of depressive disorders after surgery for acoustic neuroma, and to look for associations. Twenty seven patients with acoustic neuroma underwent thorough psychiatric assessment before surgery and at three and 12 months after surgery. Three patients had a depressive disorder in the preoperative assessment. Of the remaining 24 patients, nine (38%) had a depressive disorder at the three month check up. Deterioration of hearing was the only postoperative detriment associated with a depressive disorder (P = 0·024). All nine patients with a depressive disorder were women (P = 0·001), giving them a 69% incidence. None of the patients without preoperative depression required inpatient treatment for depressive disorder, but three patients out of nine still had a depressive disorder 12 months after surgery.
本研究的目的是确定听神经瘤手术后抑郁症的发生率和模式,并寻找相关因素。27例听神经瘤患者在手术前、术后3个月和12个月接受了全面的精神评估。术前评估中有3例患者患有抑郁症。在其余24例患者中,9例(38%)在术后3个月检查时患有抑郁症。听力下降是与抑郁症相关的唯一术后不利因素(P = 0.024)。所有9例抑郁症患者均为女性(P = 0.001),发病率为69%。术前无抑郁的患者均无需因抑郁症住院治疗,但9例患者中有3例在术后12个月仍患有抑郁症。