Shih W J, Lee J K, Milan P
Nuclear Medicine Service, Veterans Affairs Medical Center, Lexington, KY 40511, USA.
J Nucl Med. 1996 Jul;37(7):1183-5.
Technetium-99m-HMPAO and 99mTc-MIBI brain SPECT, MRI, CT and cerebral angiogram were studied in a patient with recurrent occipital meningioma. MRI and CT of the head showed right cerebral hemispheric tumor masses involving parasagittal, temporal and parietoccipital areas. The angiograms showed an intense vascular tumor blush in recurrent mass lesions supplied by the following arteries: the meningeal branch of the right external carotid artery, the right middle cerebral artery, the right anterior cerebral artery and the right posterior cerebral artery. Although demonstrable 99mTc-MIBI lesions mass exactly corresponded to CT and MRI (T-1) findings, mass lesions exhibited a mismatch between 99mTc-MIBI (increased uptake) and 99mTc-HMPAO (absent uptake) brain SPECT images. Technetium-99m-MIBI images, rather than 99mTc-HMPAO brain SPECT, resulted in the correct pathological diagnosis of recurrent meningioma.
对一名复发性枕部脑膜瘤患者进行了锝-99m-六甲基丙二胺肟（99mTc-HMPAO）和99m锝-甲氧基异丁基异腈（99mTc-MIBI）脑单光子发射计算机断层扫描（SPECT）、磁共振成像（MRI）、计算机断层扫描（CT）及脑血管造影检查。头部MRI和CT显示右侧大脑半球肿瘤肿块累及矢状旁、颞叶和顶枕部区域。血管造影显示复发性肿块病变有强烈的肿瘤血管造影剂充盈，由以下动脉供血：右侧颈外动脉脑膜支、右侧大脑中动脉、右侧大脑前动脉和右侧大脑后动脉。尽管可显示的99mTc-MIBI病变肿块与CT和MRI（T-1）检查结果完全相符，但肿块病变在99mTc-MIBI（摄取增加）和99mTc-HMPAO（无摄取）脑SPECT图像上表现出不匹配。99m锝-甲氧基异丁基异腈图像而非99mTc-HMPAO脑SPECT检查结果，得出了复发性脑膜瘤的正确病理诊断。
