Schalij-Delfos N E, Zijlmans B L, Wittebol-Post D, Tan K E, Cats B P
F.C. Donders Institute of Ophthalmology, University Hospital, Utrecht, The Netherlands.
J Pediatr Ophthalmol Strabismus. 1996 Jan-Feb;33(1):35-8. doi: 10.3928/0191-3913-19960101-10.
Early detection of retinopathy of prematurity (ROP) in premature and very-low-birth-weight infants is crucial. In this retrospective study, 581 infants either with a birth weight below 1500 g or a gestational age of less than 32 weeks, or who did not fit these criteria but were judged to be at increased risk, were screened for ROP. ROP developed in 159 (27.4%). The incidence of ROP appeared to be inversely proportional to birth weight and gestational age. Infants with a birth weight below 750 g had a significantly higher risk of developing stage 3 and 4 ROP. The mean age at detection was 7.6 +/- 1.6 weeks. Nearly all of the ROP cases and all of the stage 3 and 4 cases were detected between the 5th and 10th week. Because screening should be focused on these vision-threatening stages, ophthalmic examinations should be concentrated in, but not limited to, the period between the 5th and the 10th postnatal week.
早期发现早产和极低出生体重儿的早产儿视网膜病变（ROP）至关重要。在这项回顾性研究中，对581名出生体重低于1500克或胎龄小于32周，或不符合这些标准但被判定为风险增加的婴儿进行了ROP筛查。159名（27.4%）婴儿发生了ROP。ROP的发病率似乎与出生体重和胎龄成反比。出生体重低于750克的婴儿发生3期和4期ROP的风险显著更高。检测时的平均年龄为7.6 +/- 1.6周。几乎所有的ROP病例以及所有3期和4期病例都是在第5至10周之间发现的。由于筛查应集中在这些威胁视力的阶段，眼科检查应集中在出生后第5至10周，但不限于该时间段。
