La Grutta S, Maggio C, Giuffrè M, Carta M, Teresi S, Liotta A
Istituto di Pediatria, Università degli Studi, Palermo.
Minerva Pediatr. 1996 Jul-Aug;48(7-8):303-7.
The seric levels of IGF1 and IGFBP3 and their molar ratio, together with clinical and auxological parameters, have been evaluated in 16 patients (8 males and 8 females), of average age of 11.6 +/- 8.66 months, who were suffering from complex food allergy and were subjected to a balanced diet will excluded the "offending" food. The results, compared with those of a control population of same age and body surface, have shown a significative reduction of IGF1 and an increase of the molar ratio IGFBP3/IGF1. These observations suggest that, in spite of no significative variation of growth in height and weight, an exclusion diet for a food allergy can reduce the biological activity of some hormonal factors of growth.
对16例（8例男性和8例女性）平均年龄为11.6±8.66个月、患有复杂食物过敏且接受排除“致病”食物的均衡饮食的患者，评估了其血清IGF1和IGFBP3水平及其摩尔比，以及临床和体格学参数。与同年龄和体表面积的对照人群结果相比，显示IGF1显著降低，IGFBP3/IGF1摩尔比增加。这些观察结果表明，尽管身高和体重增长无显著变化，但食物过敏的排除饮食可降低某些生长激素因子的生物活性。
