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[使用活检和组织学研究对口腔黏膜病变进行临床、手术及诊断评估:两种方法的比较]

[Clinical, surgical and diagnostic evaluation of lesions of the oral mucosa using biopsy and histological studies: comparison of two methods].

作者信息

Campisi G, Freschi M, Lauritano D, Spadari F

机构信息

Istituto Discipline Odontostomatologiche, Ospedale San Raffaele, Milano.

出版信息

Minerva Stomatol. 1996 Jun;45(6):247-52.

PMID:8965769
Abstract

In this study, the authors evaluated the clinical and histologic efficacy of electrosurgery (DTC 100) in performing excisional biopsy on benign mucosal lesions, in comparison with traditional surgery (scalpel and suture). For this aim, 40 biopsy specimens were selected and divided into 4 distinct groups: group A1, samples of oral lesions located on the genian mucosa and removed using DTC 100; group A2, samples of healthy genian mucosa removed using DTC 100, as control; group B1, samples of oral lesions located on the genian mucosa and removed using traditional surgery; group B2, samples of healthy genian mucosa removed using traditional surgery, as control. The clinical evaluation was carried out regarding symptomatology and bleeding after surgery, healing time, restitutio ad integrum. It gives positive results for the electrosurgical technique, in which the suture is not necessary. The histologic evaluation regarding the microscopical adequacy of specimens removed by means of electrosurgery shows better results than those from other authors; in fact, the presence of the cauterized margin compromize minimally the possibility of examining specimens of adequate size; the dimension of the cauterized margin also depends on various factors: the use of only the tomic function of the electroscalpel with the correct setting; the skill of the surgeon who should apply neither pressure or resistance; the speed of incision; the use, when possible, of acicular and thin blades.

摘要

在本研究中,作者评估了电外科手术(DTC 100)在对良性黏膜病变进行切除活检时的临床和组织学疗效,并与传统手术(手术刀和缝合)进行了比较。为此,选取了40个活检标本并分为4个不同的组:A1组,位于龈黏膜上的口腔病变样本,使用DTC 100切除;A2组,使用DTC 100切除的健康龈黏膜样本,作为对照;B1组,位于龈黏膜上的口腔病变样本,使用传统手术切除;B2组,使用传统手术切除的健康龈黏膜样本,作为对照。对术后症状、出血情况、愈合时间和完全恢复情况进行了临床评估。电外科技术给出了阳性结果,该技术无需缝合。关于通过电外科手术切除的标本的显微镜下充分性的组织学评估显示,其结果优于其他作者的研究结果;事实上,烧灼边缘的存在对检查足够大小标本的可能性影响最小;烧灼边缘的尺寸还取决于多种因素:仅在正确设置下使用电刀的切割功能;外科医生的技巧,即既不应施加压力也不应施加阻力;切割速度;尽可能使用针状薄刀片。

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