De Kraker J, Hoefnagel C A, Caron H N, Vos A, Bras J, Greve J C
Academisch Medisch Centrum, locatie Emma Kinderziekenhuis/Hel Kinder AMC, afd. Kinderoncologie, Amsterdam.
Ned Tijdschr Geneeskd. 1996 Oct 5;140(40):1997-2000.
Three children with a localized pelvic neuroblastoma are presented. Because of progression and clinical signs of compression of adjacent structures therapy was necessary. Targeted radiotherapy with 131I-MIBG was used as the first mode of therapy. This new strategy proved to be feasible, effective and non-toxic. Application of 131I-MIBG as first-line therapy should be considered more often in neuroblastoma patients.
本文报告了3例局限性盆腔神经母细胞瘤患儿。由于病情进展及出现邻近结构受压的临床体征，因此需要进行治疗。131I-MIBG靶向放疗被用作首选治疗方式。这一新策略被证明是可行、有效且无毒的。在神经母细胞瘤患者中，应更频繁地考虑将131I-MIBG作为一线治疗方法。
