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[前列地尔(前列地尔α-环糊精)治疗下肢严重缺血的短期和长期评估]

[Short- and long-term evaluation of treatment of critical ischemia of the lower lim with PGE1 (alprostadyl alpha-cyclodestrine)].

作者信息

Amitrano M, Izzo M, Castaldo G, Lombardi R, Tizzano R, Bellizzi A M, Vietri G C, Sorrentino A, D'Avanzo A

机构信息

Divisione di Medicina Generale, S. Giuseppe Moscati- Avellino.

出版信息

Minerva Cardioangiol. 1996 Jul-Aug;44(7-8):391-6.

PMID:8965998
Abstract

Twenty-five patients affected by chronic lower limb obliterating arteriopathy with critical ischemia in one limb were treated with PGE1 for 4 weeks and then followed-up for one year. On day 14 of treatment three groups of patients were selected on the basis of clinical symptoms and instrumental tests; patients were subdivided into Responders, Partial Responders and Non-Responders. The results obtained were satisfactory in view of the fact that the selection into three groups enabled Partial Responders to be reclassified, in some cases by repeating the treatment cycle.

摘要

25例患有慢性下肢闭塞性动脉病且单肢严重缺血的患者接受了4周的前列地尔治疗,随后进行了一年的随访。在治疗的第14天,根据临床症状和仪器检查选择了三组患者;患者被分为反应者、部分反应者和无反应者。鉴于将患者分为三组能够在某些情况下通过重复治疗周期对部分反应者进行重新分类,所获得的结果令人满意。

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1
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Minerva Cardioangiol. 1996 Jul-Aug;44(7-8):391-6.
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