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[支气管哮喘患儿尿液中的免疫球蛋白E和嗜酸性粒细胞]

[Immunoglobulin E and eosinophils in urine of children with bronchial asthma].

作者信息

Puchnarewicz A, Zoch-Zwierz W, Porowski T

机构信息

Klinika Chorób Dzieci Akademii Medycznej w Białymstoku.

出版信息

Pediatr Pol. 1996 Jan;71(1):19-24.

PMID:8966062
Abstract

Excretion IgE and eosinophils was assayed in the urine of 25 children with bronchial asthma during attack (I) after regression of symptoms (II) and in a group of healthy children aged 4-15 years. Three healthy children (12%) excreted trace amounts of IgE and single eosinophils to urine. In the group of sick children during attack (I), 20 children (80%) excreted IgE in urine, 10 children (40%) excreted eosinophils. Thirteen children (52%) had nocturia, dysuria or erythrocyturia of unknown cause. After regression of acute symptoms of asthma (II) IgE in urine was excreted in smaller amounts than in (I) by 60% of the children, while eosinophils by 24% children. In the II investigation, 8 children (32%) still had nocturia. It was found that IgE and eosinophils are present in the urine of children with bronchial asthma, regardless if symptoms from the urinary tract are present or not.

摘要

对25名支气管哮喘患儿发作期(I)、症状消退后(II)的尿液以及一组4至15岁健康儿童的尿液进行了IgE和嗜酸性粒细胞排泄检测。3名健康儿童(12%)尿中排泄微量IgE和单个嗜酸性粒细胞。在患病儿童发作期(I)组中,20名儿童(80%)尿中排泄IgE,10名儿童(40%)排泄嗜酸性粒细胞。13名儿童(52%)有无原因的夜尿、排尿困难或红细胞尿。哮喘急性症状消退后(II),60%的儿童尿中排泄的IgE量比(I)期少,24%的儿童排泄的嗜酸性粒细胞量减少。在II期检查中,8名儿童(32%)仍有夜尿。研究发现,支气管哮喘患儿的尿液中存在IgE和嗜酸性粒细胞,无论是否存在泌尿系统症状。

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