Lamka J, Suchý J, Staud F
Faculty of Pharmacy Charles University, Hradec Králové, Czech Republic.
Vet Med (Praha). 1996 Aug;41(8):251-4.
Hypodermosis and cephenemyiosis are largely widespread diseases in roe deer in the conditions of the Czech Republic. Both kinds of parasitosis cause great losses of game. The aim of this study was to test peroral administration of ivermectin with respect to the control of larval stages of hypodermosis (Hypoderma diana B.) in roe deer. Studies were performed on three localities within one three-year study and two 18-month studies. Ivermectin was administered for two days at a daily dose of 0.30 mg/kg body weight during winter game feeding. The shot deer were checked for the presence of larvae throughout the year. Prevalence and intensity of infection were determined. A total of 147 animals were checked in 1992-1994 (Tab.I); prevalence and intensity of infection were very low in comparison with the situation before treatment and with the control group (1994). Similar results were obtained in both shorter studies (Tab. II) performed on 27 animals in total. The results suggest (on the base of detail discussion) that the low values of prevalence and intensity of infection should be taken as partly distorted due to the methodical conditions of checks. The efficacy of ivermectin treatment was complemented by observation of several cases and their results employing direct checks of shot deer (Tab. III), including a six-year observation of a group of 6 to 10 individuals of tame deer treated year by. These results explicitly document the high efficacy of mass peroral ivermectin administration in the control of warble fly larvae. Ivermectin is the first drug suitable for the treatment of roe deer hypodermosis.
在捷克共和国的环境下,皮下蝇蛆病和脑包虫病是狍子中广泛传播的疾病。这两种寄生虫病都会给猎物造成巨大损失。本研究的目的是测试口服伊维菌素对控制狍子皮下蝇蛆病(Hypoderma diana B.)幼虫阶段的效果。研究在一个为期三年的研究以及两个为期18个月的研究中的三个地点进行。在冬季猎物喂食期间,伊维菌素以每日0.30毫克/千克体重的剂量连续给药两天。对射杀的鹿全年检查幼虫的存在情况。确定感染率和感染强度。1992年至1994年共检查了147只动物(表I);与治疗前的情况和对照组(1994年)相比,感染率和感染强度非常低。在总共对27只动物进行的两项较短研究(表II)中也获得了类似结果。结果表明(基于详细讨论),由于检查的方法条件,感染率和感染强度的低值应被视为部分失真。通过观察几个病例及其对射杀鹿进行直接检查的结果(表III)补充了伊维菌素治疗的效果,包括对一组6至10只每年接受治疗的驯养鹿进行的为期六年的观察。这些结果明确证明了口服伊维菌素大规模给药在控制皮蝇幼虫方面的高效性。伊维菌素是第一种适用于治疗狍子皮下蝇蛆病的药物。