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[食物过敏中的嗜酸性粒细胞性胃肠炎]

[Eosinophilic gastroenteritis in food allergy].

作者信息

Pfaffenbach B, Adamek R J, Bethke B, Stolte M, Wegener M

机构信息

Medizinische Universitätsklinik, St. Josef-Hospital, Ruhr-Universität Bochum.

出版信息

Z Gastroenterol. 1996 Aug;34(8):490-3.

PMID:8967122
Abstract

A 23-year-old woman suffered from chronic abdominal pain, nausea and diarrhea. The clinical symptoms particularly increased after ingestion of several foods. Laboratory investigation revealed a moderate eosinophilia in peripheral blood, elevated serum IgE-level and specific IgE against food allergens in radioallergosorbent testing. The patient exhibited exsudative ascites with eosinophiles. CT scan revealed a thickened wall of the small bowel. There was no evidence of a parasitic or extraintestinal disease. Endoscopically, the gastrointestinal tract appeared normal. Histological examinations of biopsies of the gastrointestinal tract led to the diagnosis of eosinophilic gastroenteritis. Under an elimination diet the patient is symptom-free since 16 months without ascites.

摘要

一名23岁女性患有慢性腹痛、恶心和腹泻。摄入几种食物后,临床症状尤其加重。实验室检查显示外周血嗜酸性粒细胞中度增多、血清IgE水平升高,且在放射变应原吸附试验中对食物过敏原呈特异性IgE阳性。患者出现含嗜酸性粒细胞的渗出性腹水。CT扫描显示小肠壁增厚。没有寄生虫或肠外疾病的证据。内镜检查显示胃肠道外观正常。胃肠道活检的组织学检查确诊为嗜酸性粒细胞性胃肠炎。采用排除饮食后,患者16个月来无症状,且无腹水。

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