Perdigão C
U.T.I.C - Arsénio Cordeiro, Hospital de Santa Maria/Faculdade de Medicina de Lisboa.
Acta Med Port. 1996 Feb-Mar;9(2-3):113-9.
The morphological bases which condition left ventricular disfunction after acute myocardial infarction as well as the concepts of expansion and remodelling of the myocardium are reviewed. The clinical aspects indicating ventricular disfunction are presented and several pharmacological effects which have been proposed for the prevention of this situation. Particular emphasis is given to the role of angiotensin-converting enzyme inhibitors in the prevention of left ventricular disfunction after acute myocardial infarctions, based on the most recent clinical trials.
本文综述了急性心肌梗死后导致左心室功能障碍的形态学基础以及心肌扩张和重塑的概念。介绍了提示心室功能障碍的临床方面，并提出了几种预防这种情况的药理作用。基于最近的临床试验，特别强调了血管紧张素转换酶抑制剂在预防急性心肌梗死后左心室功能障碍中的作用。
