Genov D, Rusev R
Akush Ginekol (Sofiia). 1996;35(1-2):26-8.
The present facts on immunity system in women with endometriosis are quite contradictory. We investigated 30 women with hystological proven diagnosis, divided into three groups: 1st group-10 women with myoma uteri, 2nd group-10 women with endometriosis, 3rd group-10 women with adnexitis chronica. Control group were 65 healthy women in reproductive age between 24-42 years. It is established, that in the 3 groups cell immunity is oppressed, but more highly expressed in women with endometriosis (Tact and Ttot. p < 0.001). There are not changes in the levels of B lymphocytes, but in the women with endometriosis they are most low. In the 3 groups NBT (Nitro Blue Tetrazolium) is with high values, i. e. there is increased dynamic activity on the neutrophils. The humoral immunity (lg G, lg A, lg M) are within the borders of standard. The results suggest the concept for disturbance of cells immunity in endometriosis.
目前关于子宫内膜异位症女性免疫系统的事实相当矛盾。我们调查了30名经组织学确诊的女性,分为三组:第一组——10名患有子宫肌瘤的女性,第二组——10名患有子宫内膜异位症的女性,第三组——10名患有慢性附件炎的女性。对照组为65名年龄在24至42岁之间的育龄健康女性。结果表明,三组的细胞免疫均受到抑制,但在子宫内膜异位症女性中表达更为明显(Tact和Ttot,p < 0.001)。B淋巴细胞水平没有变化,但在子宫内膜异位症女性中最低。三组的NBT(硝基蓝四氮唑)值较高,即中性粒细胞的动态活性增强。体液免疫(lg G、lg A、lg M)在正常范围内。结果提示了子宫内膜异位症细胞免疫紊乱的概念。