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[胃肠道手术干预前后患者的肝功能及脂质代谢状况]

[Liver function and the lipid metabolic status of patients before and after a surgical intervention on the gastrointestinal tract].

作者信息

Vasil'kov V G, Kurashvili L V, Kelina N Iu, Artem'eva L O

出版信息

Anesteziol Reanimatol. 1996 May-Jun(3):21-5.

PMID:8967611
Abstract

Local hepatic bloodflow (LHB) and metabolic processes were examined in patients with abdominal diseases during intensive transfusion and infusion therapy attended by incomplete parenteral feeding. A reduction of LHB and disorders of lipid metabolism were observed before surgery. After surgery LHB was still reduced on days 1-3. Cholestatic and cytolytic syndromes developed after the intervention, and a reduction of the protein-synthesizing function of hepatocytes and disorders of the lipid status were observed. By days 7-10 the protein-synthesizing function recovered, as did the enzymatic activity, but no complete recovery of LHB and lipid spectrum were observed.

摘要

在不完全肠外营养支持下的强化输血和输液治疗期间,对患有腹部疾病的患者的局部肝血流(LHB)和代谢过程进行了检查。术前观察到LHB减少和脂质代谢紊乱。术后第1 - 3天LHB仍降低。干预后出现胆汁淤积和细胞溶解综合征,观察到肝细胞蛋白质合成功能降低和脂质状态紊乱。到第7 - 10天,蛋白质合成功能恢复,酶活性也恢复,但未观察到LHB和脂质谱完全恢复。

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