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脑肿瘤的临床特征和生物标志物

Clinical features and biological markers of brain tumors.

作者信息

Castello M A, Cappelli C

机构信息

Servizio Speciale di Oncologia Pediatrica, Università degli Studi La Sapienza, Rome, Italy.

出版信息

Ann Ist Super Sanita. 1996;32(1):151-7.

PMID:8967718
Abstract

Brain tumors represent a wide and important field of oncology. Their incidence has increased in the last twenty years but the reason for this, as well as the etiopathogenesis of these tumors, has not been clearly understood yet. In the first part of this paper we have divided brain tumors on a topographic basis in neoplasms which develop in the posterior fossa, in the midbrain and in the hemispheres; the clinical characteristics of the most frequent tumors are also analysed. Particular attention has been given to neoplasms in children. In the second part we deal with the two most useful methods of diagnosis and classification of brain tumors: immunoistochemical markers and biochemical markers.

摘要

脑肿瘤是肿瘤学中一个广泛且重要的领域。在过去二十年中,其发病率有所上升,但造成这种情况的原因以及这些肿瘤的病因发病机制尚未完全明确。在本文的第一部分,我们根据肿瘤的发生部位,将脑肿瘤分为在后颅窝、中脑和大脑半球发生的肿瘤,并分析了最常见肿瘤的临床特征,特别关注了儿童肿瘤。在第二部分中,我们讨论了脑肿瘤诊断和分类的两种最有用的方法:免疫组化标志物和生化标志物。

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