Filonov A E, Manzeniuk I N, Svetoch E A
Antibiot Khimioter. 1996 Mar;41(3):20-4.
Conjugative transfer of the incompatibility group plasmids Inc P-2, Inc P-3, Inc P-4 and Inc P-5 as well as the plasmids of Pseudomonas sp. of an unknown incompatibility group to the cells of Pseudomonas mallei C-5 was shown possible for the first time. The inheritance of the transferred plasmids and the expression of the markers of resistance to antibacterial drugs were stable. Clones with reserved virulence, lowered virulence and no virulence were detected among the transconjugants. The results of the immunization by the avirulent cells of P. mallei C-5 (RP4) were evident of low immunogenic capacity of the microbe.
首次证明，不相容群质粒Inc P-2、Inc P-3、Inc P-4和Inc P-5以及未知不相容群的假单胞菌属质粒可接合转移至鼻疽假单胞菌C-5细胞。转移质粒的遗传性以及对抗菌药物耐药标记的表达是稳定的。在接合子中检测到了具有保留毒力、降低毒力和无毒力的克隆。用鼻疽假单胞菌C-5（RP4）无毒细胞进行免疫的结果表明该微生物的免疫原性较低。
