基于两亲性聚醚二醇的嵌段聚氨酯的合成与表征

Synthesis and characterization of segmented polyurethanes based on amphiphilic polyether diols.

作者信息

Lan P N, Corneillie S, Schacht E, Davies M, Shard A

机构信息

University of Gent, Department of Organic Chemistry, Belgium.

出版信息

Biomaterials. 1996 Dec;17(23):2273-80. doi: 10.1016/0142-9612(96)00056-7.

DOI:10.1016/0142-9612(96)00056-7

PMID:8968523

Abstract

Segmented polyurethanes (SPUs) based on polyethylene glycol (PEG), polypropylene glycol (PPG) and a series of Pluronics with different ethylene oxide/propylene oxide ratios (EO/PO) and molecular weights were prepared. Different diisocyanates were used for making SPUs: 4,4-diphenylmethane diisocyanate (MDI), 4,4-dicyclohexylmethane diisocyanate (MDCI), hexamethylene diisocyanate (HMDI) and isophorone diisocyanate (IPDI). 1,4-Butane diol (BD) and ethylene diamine (ED) were used as chain extenders. The polymers obtained were characterized by infrared spectroscopy (IR), nuclear magnetic resonance (NMR) and differential scanning calorimetry (DSC). The microphase morphology (phase separation and phase mixing) is discussed in more detail.

摘要

制备了基于聚乙二醇（PEG）、聚丙二醇（PPG）以及一系列具有不同环氧乙烷/环氧丙烷比例（EO/PO）和分子量的普朗尼克的分段聚氨酯（SPU）。使用不同的二异氰酸酯来制备SPU：4,4'-二苯基甲烷二异氰酸酯（MDI）、4,4'-二环己基甲烷二异氰酸酯（MDCI）、六亚甲基二异氰酸酯（HMDI）和异佛尔酮二异氰酸酯（IPDI）。1,4-丁二醇（BD）和乙二胺（ED）用作扩链剂。通过红外光谱（IR）、核磁共振（NMR）和差示扫描量热法（DSC）对所得聚合物进行了表征。更详细地讨论了微相形态（相分离和相混合）。