Wang Peng, Luo Jianbin, Du Minhui, He Chengsheng, Fan Cuirong, Zhong Yinping
Department of Polymer Material Science Engineering, Sichuan University, Chengdu, China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2005 Aug;22(4):734-8.
Adopting the two-step method and changing the proportion between PEG (Polyethylene glycol) and PTMG (poly (tetrahydrofuran), we used the MDI (4,4'-diphenylmethane diisocyanate) and short chain extender BDO (1,4-butanediol) as hard segment, the PTMG and PEG as soft segment, and hence prepared a series of polyether-based thermoplastic polyurethanes. FTIR showed the structure character of these polyurethanes. The determination of mechanics property and water contact angles revealed their good mechanics properties and hydrophilicity. Blood compatibility was evaluated by hemolysis test and platelet adhesion test, which revealed their good hemocompatibility. So those polyurethanes may be of wide application in the future.
采用两步法并改变聚乙二醇(PEG)与聚四氢呋喃(PTMG)之间的比例,我们使用4,4'-二苯基甲烷二异氰酸酯(MDI)和短链扩链剂1,4-丁二醇(BDO)作为硬段,聚四氢呋喃(PTMG)和聚乙二醇(PEG)作为软段,从而制备了一系列聚醚基热塑性聚氨酯。傅里叶变换红外光谱(FTIR)显示了这些聚氨酯的结构特征。力学性能和水接触角的测定揭示了它们良好的力学性能和亲水性。通过溶血试验和血小板黏附试验评估血液相容性,结果表明它们具有良好的血液相容性。因此,这些聚氨酯在未来可能具有广泛的应用。