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二尖瓣狭窄的缓解。心脏外科手术中的历史性一步。

The relief of mitral stenosis. An historic step in cardiac surgery.

作者信息

Khan M N

机构信息

University of Texas Medical School, Houston, 77030, USA.

出版信息

Tex Heart Inst J. 1996;23(4):258-65; discussion 265-6.

Abstract

Significant progress has been achieved in cardiac surgery in the last 50 years. Mitral valve surgery (especially for the relief of mitral stenosis) has paralleled the innovations and trends of cardiac surgery and often has served as the benchmark of the latest procedures and techniques. A chronological survey of mitral valve surgery is presented, with emphasis on parallels to cardiac surgery in general and with highlights of key figures and events that have conclusively altered the surgeon's approach to and success with cardiac dysfunction. A few surgeons promulgated the idea of cardiac surgery in the late 19th century, but mitral valve surgeries were not performed in earnest until Souttar's and Cutler's initial attempts in the 1920s and were not successful on large groups of patients until Bailey and Harken made independent breakthroughs in the 1940s, finally laying to rest the idea of the "inviolable heart." Cardiopulmonary bypass provided cardiac surgeons with the time to implant mechanical and bioprosthetic valves for palliative benefit to patients. The "perfect" valve has yet to be found, but the Starr-Edwards mechanical valve since its inception in 1961 has been one of the most successful and widely used prosthetic valves. Gradual improvement in surgical technique and growing knowledge of valve function enabled the re-emergence of mitral valve repair in the 1980s as the preferred surgical method of treating mitral stenosis. In the last 10 years, mitral valve balloon dilation has provided a nonsurgical technique for relief of stenosis and represents the broader trend towards interventional techniques.

摘要

在过去的50年里,心脏外科手术取得了重大进展。二尖瓣手术(尤其是为缓解二尖瓣狭窄)与心脏外科手术的创新和趋势同步发展,并且常常成为最新手术程序和技术的基准。本文按时间顺序对二尖瓣手术进行了综述,重点是与心脏外科手术的总体对比,以及那些最终改变外科医生治疗心脏功能障碍方法和成功率的关键人物和事件。19世纪后期,少数外科医生提出了心脏外科手术的想法,但直到20世纪20年代索塔尔和卡特勒首次尝试,二尖瓣手术才真正开展起来,直到20世纪40年代贝利和哈肯取得独立突破,才在大量患者身上取得成功,最终打消了“心脏不可侵犯”的观念。体外循环为心脏外科医生提供了时间,以便为患者植入机械瓣膜和生物瓣膜,以达到姑息治疗的目的。“完美”的瓣膜尚未找到,但自1961年问世以来,斯塔尔-爱德华兹机械瓣膜一直是最成功、使用最广泛的人工瓣膜之一。手术技术的逐步改进和对瓣膜功能认识的不断提高,使得二尖瓣修复术在20世纪80年代重新成为治疗二尖瓣狭窄的首选手术方法。在过去10年里,二尖瓣球囊扩张术为缓解狭窄提供了一种非手术技术,代表了介入技术的更广泛趋势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecd1/337096/46823aa9fd2b/thij00031-0013-a.jpg

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Ann Surg. 1958 May;147(5):636-44; discussion 644-5. doi: 10.1097/00000658-195805000-00007.

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