Roushdi I M, Mikhail A A, Chaaban I
Pharmazie. 1977 May;32(5):269-70. doi: 10.1002/chin.197741209.
Compounds were prepared through the reaction of benzoquinone, naphthoquinone and 2-methyl-1.4-naphthoquinone with several sulphonamides in common use. It is hoped that incorporation of these bacteriostatic agents with the high lipid solubility of the quinone used may afford a better bacteriostatic activity. Determination of the partition coefficient of some representative samples proved these compounds to have high lipid solubility.
通过苯醌、萘醌和2-甲基-1,4-萘醌与几种常用的磺胺类药物反应制备化合物。人们希望将这些抑菌剂与所用醌的高脂溶性相结合，可能会产生更好的抑菌活性。对一些代表性样品的分配系数测定证明这些化合物具有高脂溶性。
