[Structure-activity relationship in Mannich bases with and without nitrogen mustard groups and in various reduction products derived from beta-aminoketones as evidenced with the aid of a cancerostatic 3-step test using transplantation tumors].
作者信息
Werner W, Jungstand W, Gutsche W, Wohlrabe K
出版信息
Pharmazie. 1977 Jun 6;32(6):341-7.
PMID:896938
Abstract
摘要
相似文献
1
2
3
4
Resarch on new Schiff bases with antiblastic activity. Carcinostatic activities of 3-p-(2',5'-dimethoxy-4'-(N,N-bis( -chloroethyl)-amino)benzylideneamino)phenyl-2-oxazolidinone (GEA 29 = BAY a 5850).具有抗胚细胞活性的新型席夫碱的研究。3-对-(2',5'-二甲氧基-4'-(N,N-双(β-氯乙基)-氨基)亚苄基氨基)苯基-2-恶唑烷酮（GEA 29 = BAY a 5850）的抗癌活性。
Farmaco Sci. 1971 Sep;26(9):784-804.
5
[Correlations between the chemical structure of Mannich bases with and without nitrogen mustard groups and their cytostatic effect on Ehrlich ascites carcinoma in albino mice].
Arzneimittelforschung. 1970 Feb;20(2):246-9.
6
bis-Mannich bases of styryl ketones as antileukemic agents.作为抗白血病药物的苯乙烯基酮双曼尼希碱
Neoplasma. 1985;32(1):85-91.
7
Some antitumor agents derived from benzaldehyde nitrogen mustards.一些抗肿瘤药物源自苯甲醛氮芥。
Acta Pharm Suec. 1970 Apr;7(2):87-104.
8
9
Synthesis and cytotoxic evaluation of some Mannich bases of alicyclic ketones.一些脂环族酮的曼尼希碱的合成与细胞毒性评价
Pharmazie. 1995 Oct;50(10):668-71.
10
Beta-aminoketones as prodrugs with pH-controlled activation.
Int J Pharm. 2007 May 24;336(2):208-14. doi: 10.1016/j.ijpharm.2006.11.055. Epub 2006 Dec 1.
Zotero 插件