Bjørnstad K, Duran R M, Nassau K G, Gometza B, Hatle L K, Duran C M
Department of Cardiovascular Diseases, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
Am Heart J. 1996 Dec;132(6):1173-8. doi: 10.1016/s0002-8703(96)90460-3.
Eighty-six patients, mean age 29 +/- 15 years, underwent aortic valve reconstruction with bovine or autologous pericardial tissue. Mean clinical follow-up was 35 months. Echocardiographic data were assessed in 65 patients with follow-up > or = 6 months. There were two in-hospital and three late deaths. Warfarin was not given, and no thromboembolic events occurred. Five (6%) patients needed reoperation because of severe aortic regurgitation. Peak aortic valve gradients remained low (26 +/- 14 mm Hg for the bovine group and 16 +/- 16 mm Hg for the autologous group). One patient is awaiting surgery for aortic stenosis after 76 months. Leaflet thickening at latest follow-up was marked in six (9%) patients. Left ventricular dimensions normalized postoperatively and showed only insignificant increase during follow-up. This technique is a promising alternative to valve prosthesis in selected patients; however, longer follow-up is necessary to assess long-term results.
86例患者，平均年龄29±15岁，接受了牛心包或自体心包组织的主动脉瓣重建术。平均临床随访时间为35个月。对65例随访时间≥6个月的患者进行了超声心动图数据评估。有2例院内死亡和3例晚期死亡。未给予华法林，未发生血栓栓塞事件。5例（6%）患者因严重主动脉瓣反流需要再次手术。主动脉瓣峰值梯度仍较低（牛心包组为26±14 mmHg，自体心包组为16±16 mmHg）。1例患者在76个月后等待主动脉瓣狭窄手术。在最近一次随访中，6例（9%）患者出现明显的瓣叶增厚。左心室尺寸术后恢复正常，随访期间仅出现轻微增加。对于选定的患者，该技术是瓣膜置换术的一种有前景的替代方法；然而，需要更长时间的随访来评估长期结果。
