Gliozheni E, Picano E, Bernardino L, Pingitore A, Sicari R, Marzilli M
Institute of Clinical Physiology, C.N.R., Pisa, Italy.
Am J Cardiol. 1996 Dec 15;78(12):1419-24. doi: 10.1016/s0002-9149(97)89294-6.
In patients with a major coronary vessel occluded, the presence of good coronary collateral circulation increases vulnerability to myocardial ischemia induced by pharmacologic coronary vasodilation. The presence of good collaterals results in a greater frequency, severity, and extent of dipyridamole-induced regional left ventricular dysfunction, consistent with the hypothesis of angiographically assessed collaterals facilitating "steal phenomena" during dipyridamole-induced coronary vasodilation.
在主要冠状动脉血管闭塞的患者中，良好的冠状动脉侧支循环的存在会增加因药物性冠状动脉血管扩张诱发心肌缺血的易感性。良好侧支循环的存在导致双嘧达莫诱发的局部左心室功能障碍的频率、严重程度和范围更大，这与血管造影评估的侧支循环在双嘧达莫诱发冠状动脉血管扩张期间促进“窃血现象”的假说一致。
