Baron P L
Department of Surgery, Medical University of South Carolina, Charleston 29425, USA.
Semin Oncol. 1996 Dec;23(6):714-8.
It is critical for physicians who may play a role in the diagnosis of melanoma to be knowledgeable of how to approach a suspicious nevus. A full thickness of tissue is necessary to microstage the melanoma and thereby guide subsequent treatment decisions. The past two decades have witnessed a dramatic change in the surgical management of this disease in that the margin of excision seems to be constantly shrinking. Well-conducted randomized studies have shown conclusively that narrower margins are sufficient for thin and intermediate thickness melanomas. Thus, the survival is comparable with that achieved for more radical excisions with less functional and cosmetic deficit.
对于可能参与黑色素瘤诊断的医生来说，了解如何处理可疑痣至关重要。对黑色素瘤进行微分期需要完整厚度的组织，从而指导后续的治疗决策。在过去二十年中，这种疾病的手术治疗发生了巨大变化，即切除边缘似乎在不断缩小。精心设计的随机研究已确凿表明，较窄的边缘对于薄型和中等厚度的黑色素瘤就足够了。因此，其生存率与更广泛切除所达到的生存率相当，且功能和美容缺陷更少。
