Elias C J, Coggins C
Population Council, Bangkok, Thailand.
AIDS. 1996 Dec;10 Suppl 3:S43-51.
THE NEED FOR PREVENTION: Women throughout the world face a growing risk of infection with HIV. Consistent condom use, one cornerstone of primary prevention strategy, is not always feasible for many women. Consequently, women urgently need infection prevention technology that is within their personal control.
This session will review current efforts to develop and test female-controlled methods for preventing sexual transmission of HIV and other sexually transmitted pathogens. Both physical and chemical methods will be summarized, including recent findings concerning the efficacy and acceptability of the vaginal pouch (female condom), as well as an overview of research on vaginal microbicides. Data from studies of existing over-the-counter spermicides will be reviewed. The wide range of novel microbicidal products currently being evaluated in the laboratory and early clinical trials demonstrate the breadth of possibilities presented by chemical barrier methods. However, formidible challenges face public and private sector research and development efforts. This session will conclude by highlighting several issues related to the clinical evaluation and introduction of female-controlled prevention technology.
预防的必要性：世界各地的女性感染艾滋病毒的风险日益增加。坚持使用避孕套作为一级预防策略的基石之一，对许多女性来说并不总是可行的。因此，女性迫切需要能够由她们自己掌控的感染预防技术。
本次会议将回顾目前为开发和测试女性可控的预防艾滋病毒及其他性传播病原体性传播方法所做的努力。将对物理和化学方法进行总结，包括有关阴道套（女用避孕套）有效性和可接受性的最新研究结果，以及阴道杀菌剂的研究概述。将回顾现有非处方杀精剂的研究数据。目前正在实验室和早期临床试验中评估的各种新型杀菌产品表明了化学屏障方法所展现的广泛可能性。然而，公共和私营部门的研发工作面临着巨大挑战。本次会议将通过强调与女性可控预防技术的临床评估和引入相关的几个问题来结束。
