Shinohara M, Ikebe T, Nakamura S, Takenoshita Y, Oka M, Mori M
Second Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Kyushu University, Fukuoka, Japan.
Br J Oral Maxillofac Surg. 1996 Dec;34(6):515-9. doi: 10.1016/s0266-4356(96)90248-x.
We report rare case of multiple pleomorphic adenomas arising in the parotid and submandibular lymph nodes of a 21-year-old man. These tumours were surrounded by lymphoid tissue which was almost identical to that of the cortex of lymph node. The possibility of metastasizing pleomorphic adenomas was discounted because the mitotic activity was low and there were no signs of infiltration. Heterotopic salivary gland tissue was also found in the lymph nodes that contained the tumours, and each tumour expressed a similar immunohistochemical staining pattern to that of the salivary gland tissue. These findings indicate that these pleomorphic adenomas probably arose from the salivary gland tissue within the lymph nodes.
我们报告了一例罕见病例，一名21岁男性的腮腺和下颌下淋巴结出现多发性多形性腺瘤。这些肿瘤被淋巴组织包围，该淋巴组织与淋巴结皮质的淋巴组织几乎相同。由于有丝分裂活性低且无浸润迹象，排除了多形性腺瘤转移的可能性。在含有肿瘤的淋巴结中还发现了异位唾液腺组织，每个肿瘤的免疫组化染色模式与唾液腺组织相似。这些发现表明，这些多形性腺瘤可能起源于淋巴结内的唾液腺组织。
