Tañá P, Belmonte J
Hospital General Universitario de Alicante SVS, Servicio de Oftalmologia, Spain.
J Cataract Refract Surg. 1996 Nov;22(9):1211-21. doi: 10.1016/s0886-3350(96)80070-8.
To analyze experimentally in cadaver eyes several models of commercially available posterior chamber intraocular lenses (IOLs) to determine their stability, fixation, and behavior in the capsular bag in relation to their overall size, optic diameter, shape, material, and haptic configuration.
Eye Bank and Department of Ophthalmology, University General Hospital of Alicante, Spain.
Thirty-three IOLs of different sizes, shapes, and designs, divided in two series and five groups, were implanted successively in 31 cadaver eyes. All the proceedings were videotaped, and measurements were made on the television screen with the picture static. Main outcome measures were the diameters of the lens, the empty capsular bag, and the capsulorhexis; capsular distension by the IOL haptics; extent of haptic arc of contact with the capsular equator; and IOL mobility in the bag.
The stability of and stretching caused by the IOLs varied greatly depending on their overall size, haptic flexibility, and the extent of the arc of haptic contact with the capsular equator. Lenses between 13.5 and 14.0 mm had good stability but stretched the capsule excessively. The J-loop haptic configuration produced a spindle-shaped bag deformity that might come in contact with the ciliary processes in the physiologic eye. Among IOLs designed for in-the-bag implantation after capsulorhexis, the two smaller than 12.0 mm were unstable, permitting excessive mobility in the capsular bag. Except for IOLs with a 5.0 mm optic, all 12.0 mm IOLs had reasonable stability, little or no mobility within the capsular bag, and good short-term centering. Lenses with a broad angulation at the haptic-optic junction, to about 90 degrees, achieved the largest arc of contact with the equator and behaved as lenses with larger optics. The Pharmacia 808 performed best.
After capsulorhexis and extracapsular cataract extraction, 12.0 mm, poly(methyl methacrylate), one-piece IOLs with modified C-shaped loops, 90 degree angulation at the haptic-optic junction, and an optic diameter between 6.0 and 6.5 mm performed best in the capsular bag.
通过对尸体眼进行实验分析，研究几种市售后房型人工晶状体（IOL）模型，以确定其稳定性、固定情况以及在囊袋内的表现，这些表现与它们的整体尺寸、光学直径、形状、材料和襻结构有关。
西班牙阿利坎特大学总医院眼库及眼科。
将33个不同尺寸、形状和设计的IOL分为两个系列和五个组，依次植入31只尸体眼中。所有操作均进行录像，并在图像静止的电视屏幕上进行测量。主要观察指标包括晶状体、空囊袋和撕囊口的直径；IOL襻引起的囊袋扩张；襻与囊袋赤道接触的弧度范围；以及IOL在囊袋内的活动度。
IOL的稳定性及其引起的拉伸程度因整体尺寸、襻的柔韧性以及襻与囊袋赤道接触的弧度范围不同而有很大差异。13.5至14.0毫米之间的晶状体稳定性良好，但过度拉伸了囊膜。J形襻结构导致囊袋呈纺锤形变形，在生理眼中可能会接触到睫状体。在设计用于撕囊后囊袋内植入的IOL中，两个小于12.0毫米的不稳定，在囊袋内有过度活动。除了光学直径为5.0毫米的IOL外，所有12.0毫米的IOL都有合理的稳定性，在囊袋内几乎没有或没有活动度，且短期居中良好。在襻-光学部交界处有大约90度宽角度的晶状体与赤道接触的弧度最大，表现类似于光学直径更大的晶状体。Pharmacia 808表现最佳。
在撕囊和囊外白内障摘除术后，12.0毫米、聚甲基丙烯酸甲酯、一体式、襻为改良C形环、襻-光学部交界处呈90度角且光学直径在6.0至6.5毫米之间的IOL在囊袋内表现最佳。
