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抗原诱导性气道阻塞中的支气管运动(作者译)

[Bronchomotoric in antigen induced airway obstruction (author's transl)].

作者信息

Zimmermann I, Ulmer W T

出版信息

Respiration. 1977;34(3):141-51. doi: 10.1159/000193808.

Abstract

Ascaris suum extract inhalation causes bronchoconstriction in dogs. Following this reaction, the bronchi stay oversensitive against acetylcholine for at least 7 h. Electrical stimulation of the peripheral end of a nervus vagus after cutting supports the meaning that the bronchoconstriction will be caused mainly by challenge of sensory receptors. The reflex way runs through the nervus vagus. Sensitization of the bronchial tree means sensitization of the sensory receptors. Results of the arterial blood gases correspond to earlier results which showed two parts of the bronchial tree: the vagus-controlled part is mainly respnsible for the airway resistance, the vagus-noncontrolled part is mainly responsible for the regulation of the ventilation/perfusion relationships.

摘要

猪蛔虫提取物吸入可导致犬支气管收缩。在这种反应之后,支气管对乙酰胆碱至少7小时保持超敏状态。切断迷走神经后,对其外周端进行电刺激支持了支气管收缩主要由感觉受体受刺激引起的观点。反射途径通过迷走神经。支气管树的致敏意味着感觉受体的致敏。动脉血气结果与早期结果一致,早期结果表明支气管树有两部分:受迷走神经控制的部分主要负责气道阻力,不受迷走神经控制的部分主要负责通气/灌注关系的调节。

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